2-(TERT-BUTYLDIMETHYLSILOXY)THIOPHENE - APPLICATION TO TOTAL SYNTHESES OF BOTH ENANTIOMERS OF 2',3'-DIDEOXY-4'-THIOCYTIDINE

被引：26

作者：

RASSU, G ^{[1
]}

SPANU, P ^{[1
]}

PINNA, L ^{[1
]}

ZANARDI, F ^{[1
]}

CASIRAGHI, G ^{[1
]}

机构：

[1] CNR,IST APPLICAZ TECN CHIM,I-07100 SASSARI,ITALY

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 11期

关键词：

D O I：

10.1016/0040-4039(95)00162-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Exploiting novel 2-(tert-butyldimethylsiloxy)thiophene (1, TBSOT) as versatile carbon nucleophile and both enantiomers of glyceraldehyde acetonide as chiral sources, an entry to both enantiomers of anti HIV-active 2',3'-dideoxy-4'-thiocytidine 10 and ent-10 was devised and executed.

引用

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页码：1941 / 1944

页数：4

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