共 11 条
[11]
ZACHARIAS FJ, 1971, POSTGRAD MED J S, V47, P75
DOUBLE-BLIND CROSSOVER COMPARISON OF PINDOLOL, METOPROLOL, ATENOLOL AND LABETALOL IN MILD TO MODERATE HYPERTENSION
被引：53
作者：
MCNEIL, JJ
LOUIS, WJ
机构：
关键词：
D O I：
10.1111/j.1365-2125.1979.tb04774.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
1 This study was designed to compare in a double‐blind randomized crossover trial, atenolol, labetalol, metoprolol and pindolol. Considerable differences in dose (atenolol 138 +/‐ 13 mg daily; labetalol 308 +/‐ 34 mg daily; metoprolol 234 +/‐ 22 mg daily; and pindolol 24 +/‐2 mg daily were required to produce similar antihypertensive effects. 3 The overall incidence of side‐effects was similar with atenolol, metoprolol and pindolol but was slightly less with labetalol. Sleep disturbances and abnormal dreaming patterns were most frequent with pindolol. 4 There was a significantly greater fall in pulse rate during atenolol and metoprolol treatment periods. 1979 The British Pharmacological Society
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页码：S163 / S166
页数：4
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