THE DEGRADATION OF HEME BY CARBON-TETRACHLORIDE - METABOLIC-ACTIVATION REQUIRES A FREE AXIAL COORDINATION SITE ON THE HEME IRON AND ELECTRON DONATION

被引：15

作者：

MANNO, M

KING, LJ

DEMATTEIS, F

机构：

[1] MRC LABS,TOXICOL UNIT,BIOCHEM PHARMACOL SECT,CARSHALTON SM5 4EF,SURREY,ENGLAND

[2] UNIV SURREY,DEPT BIOCHEM,GUILDFORD GU2 5XH,SURREY,ENGLAND

来源：

XENOBIOTICA | 1989年 / 19卷 / 09期

关键词：

D O I：

10.3109/00498258909043159

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：1023 / 1035

页数：13

共 31 条

[1]

ANDERS MW, 1985, MICROSOMES DRUG OXID, P274

[2] CARBON-TETRACHLORIDE AND 2-ISOPROPYL-4-PENTENAMIDE-INDUCED INACTIVATION OF CYTOCHROME-P-450 LEADS TO HEME-DERIVED PROTEIN ADDUCTS [J].

DAVIES, HW ;

BRITT, SG ;

POHL, LR .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1986, 244 (01) :387-392

[3] IMMUNOCHEMICAL IDENTIFICATION OF AN IRREVERSIBLY BOUND HEME-DERIVED ADDUCT TO CYTOCHROME-P-450 FOLLOWING CCL4 TREATMENT OF RATS [J].

DAVIES, HW ;

SATOH, H ;

SCHULICK, RD ;

POHL, LR .

BIOCHEMICAL PHARMACOLOGY, 1985, 34 (17) :3203-3206

[4]

De Matteis F, 1971, Biochem J, V124, P767

[5] SELF-CATALYZED, O2-INDEPENDENT INACTIVATION OF NADPH-REDUCED OR DITHIONITE-REDUCED MICROSOMAL CYTOCHROME-P-450 BY CARBON-TETRACHLORIDE [J].

DEGROOT, H ;

HAAS, W .

BIOCHEMICAL PHARMACOLOGY, 1981, 30 (16) :2343-2347

[6] STUDIES ON THE BIOSYNTHESIS OF BLOOD PIGMENTS .1. HAEM SYNTHESIS IN HAEMOLYSED ERYTHROCYTES OF CHICKEN BLOOD [J].

DRESEL, EIB ;

FALK, JE .

BIOCHEMICAL JOURNAL, 1954, 56 (01) :156-163

[7]

FALK JE, 1964, PORPHYRINS METALLOPO, V2, P133

[8]

FERNANDEZ G, 1982, RES COMMUN CHEM PATH, V35, P283

[9] STUDIES OF PORPHYRIN SYNTHESIS IN FIBROBLASTS OF PATIENTS WITH CONGENITAL ERYTHROPOIETIC PORPHYRIA AND ONE PATIENT WITH HOMOZYGOUS COPROPORPHYRIA [J].

GRANDCHAMP, B ;

DEYBACH, JC ;

GRELIER, M ;

DEVERNEUIL, H ;

NORDMANN, Y .

BIOCHIMICA ET BIOPHYSICA ACTA, 1980, 629 (03) :577-586

[10] DEGRADATION OF CYTOCHROME-P-450 HEME BY CARBON-TETRACHLORIDE AND 2-ALLYL-2-ISOPROPYLACETAMIDE IN RAT-LIVER INVIVO AND INVITRO - INVOLVEMENT OF NON-CARBON MONOXIDE-FORMING MECHANISMS [J].

GUZELIAN, PS ;

SWISHER, RW .

BIOCHEMICAL JOURNAL, 1979, 184 (03) :481-489

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