DIFFERENTIAL-DIAGNOSIS OF CUTANEOUS LARGE CELL LYMPHOMAS USING MONOCLONAL-ANTIBODIES REACTIVE IN PARAFFIN-EMBEDDED SKIN BIOPSY SPECIMENS

被引：8

作者：

BELJAARDS, RC ^{[1
]}

MEIJER, CJLM ^{[1
]}

SCHEFFER, E ^{[1
]}

VANDERVALK, P ^{[1
]}

WILLEMZE, R ^{[1
]}

机构：

[1] FREE UNIV AMSTERDAM HOSP,DEPT PATHOL,1007 MB AMSTERDAM,NETHERLANDS

来源：

AMERICAN JOURNAL OF DERMATOPATHOLOGY | 1991年 / 13卷 / 04期

关键词：

CUTANEOUS LYMPHOMA; IMMUNOHISTOCHEMISTRY; FORMALIN FIXATION;

D O I：

10.1097/00000372-199108000-00004

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We studied a large panel of monoclonal antibodies reactive on routinely processed paraffin-embedded tissue to determine their sensitivity and specificity in the diagnosis of 35 primary cutaneous large cell lymphomas of B-(n = 14) and T-cell origin (n = 21). The findings show that differentiation between clinically relevant subgroups can be obtained by a small panel of antibodies including L26, MB2, LN1, MT1, UCHL1, and Ber-H2. Pitfalls in the use of the reagents are discussed.

引用

页码：342 / 349

页数：8

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