SINCLAIR MINIATURE SWINE - AN ANIMAL-MODEL OF HUMAN-MELANOMA

被引：54

作者：

MISFELDT, ML

GRIMM, DR

机构：

[1] Molecular Microbiology and Immunology, School of Medicine, University of Missouri-Columbia, Columbia

来源：

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY | 1994年 / 43卷 / 1-3期

关键词：

D O I：

10.1016/0165-2427(94)90133-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Sinclair swine display cutaneous melanoma lesions and develop a generalized depigmentation subsequent to tumor regression. Sinclair swine represent a valuable animal model to study the factors influencing the development of melanoma and also the factors which lead to the development of vitiligo. Therefore, information obtained in studies of Sinclair swine should facilitate our understanding of the mechanisms by which melanoma and vitiligo develop and provide us with possible therapeutic treatments for these human diseases.

引用

页码：167 / 175

页数：9