ELECTRON IONIZATION MASS-SPECTRA OF SOME CYCLOHEXANE FUSED 2-N-PHENYLIMINOPERHYDRO-1,3-OXAZINES AND RELATED THIAZINES

被引：19

作者：

PIHLAJA, K

LOTJONEN, L

FULOP, F

BERNATH, G

VAINIOTALO, P

机构：

[1] Department of Chemistry, University of Turku, Turku

[2] Institute of Pharmaceutical Chemistry, University Medical School, Szeged

[3] Department of Chemistry, University of Joensuu, Joensuu, SF-80101

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1990年 / 4卷 / 08期

关键词：

D O I：

10.1002/rcm.1290040804

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The 70 eV electron ionization mass spectra of six cyclohexane fused 2‐N‐phenyliminoperhydro‐1,3‐oxazines and six related thiazines were recorded and their fragmentation patterns were studied by metastable‐ion analysis and exact mass measurement. All the compounds examined lost a hydrogen atom from their molecular ion in a process best described as intramolecular cyclization. The most typical fragmentations were the loss of various alkyl radicals from the M+· or [MH]+ ions with the simultaneous migration of one or more hydrogen atoms from the carbocyclic part to the heterocyclic part of the molecule. N‐Substitution clearly affected the type and extent of different reactions. In general, the fragmentation patterns of the thiazine derivatives were more complicated than those of the related oxazines. In all cases studied, the cis‐ and trans‐fused isomers gave rise to so similar spectra that their adequate differentiation was not possible. Copyright © 1990 John Wiley & Sons Limited

引用

页码：279 / 282

页数：4

共 16 条

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