BETA-GLUCAN BIOSYNTHESIS INHIBITORS ISOLATED FROM FUNGI AS HYPHAL MALFORMATION INDUCER

被引：26

作者：

FUKUSHIMA, Y ^{[1
]}

SAKAGAMI, Y ^{[1
]}

MARUMO, S ^{[1
]}

机构：

[1] NAGOYA UNIV,DEPT AGR CHEM,CHIKUSA KU,NAGOYA 46401,JAPAN

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 06期

关键词：

D O I：

10.1016/S0960-894X(00)80319-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three hyphal malformation inducers were isolated from fungi and their structures identified as (+)-isoepoxydon (1), brefeldin A (2) and ophiobolin A (4), respectively. Two of them, 1 and 4, were shown to be beta-1,3-glucan synthetase inhibitors.

引用

页码：1219 / 1222

页数：4

共 13 条

[1] CELL WALL CHEMISTRY MORPHOGENESIS AND TAXONOMY OF FUNGI [J].

BARTNICK.S .

ANNUAL REVIEW OF MICROBIOLOGY, 1968, 22 :87-+

[2]

BETTINA V, 1964, J ANTIBIOT, V17, P93

[3]

Eleanor M. S., 1980, J BIOL CHEM, V255, P888

[4]

FINCHER GB, 1981, ENCY PLANT PHYSL B, V13, P68

[5] STUDIES ON POLYOXINS, ANTIFUNGAL ANTIBIOTICS .13. STRUCTURE OF POLYOXINS [J].

ISONO, K ;

ASAHI, K ;

SUZUKI, S .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1969, 91 (26) :7490-+

[6]

NAGASAWA H, 1974, AGR BIOL CHEM TOKYO, V42, P1303

[7] STRUCTURE OF OPHIOBOLIN A C25 TERPENOID HAVING A NOVEL SKELETON [J].

NOZOE, S ;

MORISAKI, M ;

TSUDA, K ;

IITAKA, Y ;

TAKAHASHI, N ;

TAMURA, S ;

ISHIBASHI, K ;

SHIRASAKA, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1965, 87 (21) :4968-+

[8] STUDIES ON METABOLITES OF COCHLIOBOLUS MIYABEANUS .I. OPHIOBOLOSIN A AND OPHIOBOLOSIN B [J].

OHKAWA, H ;

TAMURA, T .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1966, 30 (03) :285-&

[9]

SEKIGUCHI J, 1979, BIOCHEM J, V182, P455

[10] ANTIVIRAL ACTIVITY OF BREFELDIN A AND VERRUCARIN A [J].

TAMURA, G ;

ANDO, K ;

SUZUKI, S ;

TAKATSUKI, A ;

ARIMA, K .

JOURNAL OF ANTIBIOTICS, 1968, 21 (02) :160-+

← 1 2 →