BETA-GLUCAN BIOSYNTHESIS INHIBITORS ISOLATED FROM FUNGI AS HYPHAL MALFORMATION INDUCER

被引：26

作者：

FUKUSHIMA, Y ^{[1
]}

SAKAGAMI, Y ^{[1
]}

MARUMO, S ^{[1
]}

机构：

[1] NAGOYA UNIV,DEPT AGR CHEM,CHIKUSA KU,NAGOYA 46401,JAPAN

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 06期

关键词：

D O I：

10.1016/S0960-894X(00)80319-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three hyphal malformation inducers were isolated from fungi and their structures identified as (+)-isoepoxydon (1), brefeldin A (2) and ophiobolin A (4), respectively. Two of them, 1 and 4, were shown to be beta-1,3-glucan synthetase inhibitors.

引用

页码：1219 / 1222

页数：4