6,9-THIAPROSTACYCLIN - STABLE AND BIOLOGICALLY POTENT ANALOG OF PROSTACYCLIN (PGI2)

被引：62

作者：

NICOLAOU, KC ^{[1
]}

BARNETTE, WE ^{[1
]}

GASIC, GP ^{[1
]}

MAGOLDA, RL ^{[1
]}

机构：

[1] UNIV PENN,DEPT CHEM,PHILADELPHIA,PA 19104

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1977年 / 99卷 / 23期

关键词：

D O I：

10.1021/ja00465a070

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：7736 / 7738

页数：3

共 20 条

[1] SYNTHESIS OF PROSTAGLANDINS E2 AND F2ALPHA FROM (15R) AND (15S) PGA2
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[2] ARTERIAL-WALLS GENERATE FROM PROSTAGLANDIN ENDOPEROXIDES A SUBSTANCE (PROSTAGLANDIN-X) WHICH RELAXES STRIPS OF MESENTERIC AND CELIAC ARTERIES AND INHIBITS PLATELET-AGGREGATION
BUNTING, S
GRYGLEWSKI, R
MONCADA, S
VANE, JR
[J]. PROSTAGLANDINS & OTHER LIPID MEDIATORS, 1976, 12 (06) : 897 - 913
[3] TOTAL SYNTHESIS OF PROSTAGLANDINS F2ALPHA AND E2 AS NATURALLY OCCURRING FORMS
COREY, EJ
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WEINSHEN.NM
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1970, 92 (02) : 397 - &
[4] SIMPLE STEREOSPECIFIC ROUTES TO 9-EPI-PROSTAGLANDIN F2-ALPHA (PGF2-BETA) AND 11-EPI-PROSTAGLANDIN F2-ALPHA
COREY, EJ
NICOLAOU, KC
SHIBASAKI, M
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1975, (16) : 658 - 659
[5] SYNTHESIS AND BIOLOGICAL PROPERTIES OF A 9,11-AZO-PROSTANOID - HIGHLY ACTIVE BIOCHEMICAL MIMIC OF PROSTAGLANDIN ENDOPEROXIDES .9.
COREY, EJ
NICOLAOU, KC
MACHIDA, Y
MALMSTEN, CL
SAMUELSSON, B
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (09) : 3355 - 3358
[6] SYNTHESIS OF VANES PROSTAGLANDIN X,6,9ALPHA-OXIDO-9ALPHA,15ALPHA-DIHYDROXYPROSTA-(Z)5,(E)13-DIENOIC ACID
COREY, EJ
KECK, GE
SZEKELY, I
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1977, 99 (06) : 2006 - 2008
[7] CRANE BH, 1977, P AM FED CLIN RES, pA337
[8] PROSTACYCLIN (PGX) IS ENDOGENOUS METABOLITE RESPONSIBLE FOR RELAXATION OF CORONARY-ARTERIES INDUCED BY ARACHIDONIC-ACID
DUSTING, GJ
MONCADA, S
VANE, JR
[J]. PROSTAGLANDINS, 1977, 13 (01): : 3 - 15
[9] SYNTHESIS OF 13,14-DEHYDROPROSTACYCLIN METHYL-ESTER - POTENT INHIBITOR OF PLATELET-AGGREGATION
FRIED, J
BARTON, J
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (06) : 2199 - 2203
[10] ARTERIAL-WALLS ARE PROTECTED AGAINST DEPOSITION OF PLATELET THROMBI BY A SUBSTANCE (PROSTAGLANDIN-X) WHICH THEY MAKE FROM PROSTAGLANDIN ENDOPEROXIDES
GRYGLEWSKI, RJ
BUNTING, S
MONCADA, S
FLOWER, RJ
VANE, JR
[J]. PROSTAGLANDINS & OTHER LIPID MEDIATORS, 1976, 12 (05) : 685 - 713

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