LONG-TERM SOMATIC SIDE-EFFECTS AND MORBIDITY IN TESTICULAR CANCER-PATIENTS

被引:52
作者
AASS, N
KAASA, S
LUND, E
KAALHUS, O
HEIER, MS
FOSSA, SD
机构
[1] NORWEGIAN RADIUM HOSP,CANC RES INST,DEPT BIOPHYS,OSLO 3,NORWAY
[2] ULLEVAL HOSP,DEPT NEUROL,OSLO 1,NORWAY
关键词
D O I
10.1038/bjc.1990.31
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In order to evaluate long-term somatic morbidity after treatment for testicular cancer 149 patients with NED ≥ 3 years answered a questionnaire. The patients had been treated with surgery only (32 patients), radiotherapy only (39 patients), cisplatin-based chemotherapy plus surgery (46 patients) or chemotherapy plus radiotherapy with or without surgery (32 patients). Raynaud-like phenomena were the most frequent side- effect occurring significantly more often after cisplatin-based chemotherapy than after surgery or radiotherapy (33/72 patients versus 5/68 patients). Peripheral sensory ‘neuropathy’ was reported by 18% of all the patients. Seventeen per cent and 11% complained of pulmonary symptoms and auditory symptoms, respectively. Gastrointestinal side-effects were more frequent after any type of cytotoxic therapy than after surgery only (34/47 patients versus 5/22 patients). Twenty-six patients had fathered children after treatment. About 80% of the patients were in full time wage-earning activity when they answered the questionnaire. In conclusion, 3-7 years after treatment for testicular cancer, 30-50% of the patients had minor somatic complaints whereas serious side-effects seldom occurred. © Macmillan Press Ltd., 1990.
引用
收藏
页码:151 / 155
页数:5
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