METABOLITES FROM A SHAKE CULTURE OF BOTRYTIS-CINEREA

被引：52

作者：

COLLADO, IG ^{[1
]}

HERNANDEZGALAN, R ^{[1
]}

DURANPATRON, R ^{[1
]}

CANTORAL, JM ^{[1
]}

机构：

[1] UNIV CADIZ,FAC CIENCIAS,DEPT MICROBIOL,E-11510 PUERTO REAL,SPAIN

来源：

PHYTOCHEMISTRY | 1995年 / 38卷 / 03期

关键词：

BOTRYTIS CINEREA; HYPHOMYCETES; METABOLITES; SESQUITERPENOIDS; DIHYDROBOTRYDIAL;

D O I：

10.1016/0031-9422(94)00690-U

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Four new metabolites, 10-oxo-dihydrobotrydial, 4 beta-acetoxy-9 beta-10 beta-15 alpha-trihydroxyprobotrydial, beta-O-methyldihydrobotrydialone and alpha-O-methyldihydrobotrydialone, were isolated from a shake culture of Botrytis cenerea. The second compound, a tricyclic sesquiterpene, is a key biosynthetic intermediate and sheds light on the last steps of the biosynthesis of botrydial derivatives. A higher oxidation level was observed in the metabolites isolated. The structures were elucidated by extensive NMR investigations of the natural compounds and their derivatives.

引用

页码：647 / 650

页数：4

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