N-ACYLETHANOLAMINE ACCUMULATION IN INFARCTED MYOCARDIUM

被引：142

作者：

EPPS, DE

SCHMID, PC

NATARAJAN, V

SCHMID, HHO

机构：

[1] The Hormel Institute, University of Minnesota, Austin

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 90卷 / 02期

关键词：

D O I：

10.1016/0006-291X(79)91281-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Long-chain N-acylethanolamines were found at levels of 400-500 nmol per g tissue in the infarcted areas of canine myocardium 24 hours after coronary artery ligation. Peripheral infarct areas also contained substantial amounts (200 nmol/g) while apparently normal heart muscle contained very little (< 10 nmol/g). The amide linked fatty acids were mainly 16:0, 18:0, 18:1 and 18:2. Because of its anti-inflammatory activity, N-acylethanolamine may exert beneficial effects in the infarcted area and may be produced as a response to ischemic injury. © 1979.

引用

页码：628 / 633

页数：6

共 21 条

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