THE RHODIUM CARBENOID ROUTE TO CYCLIC ETHERS - SYNTHESIS OF THE CIS-2,7-DISUBSTITUTED OXEPANE SKELETON OF ISOLAUREPINNACIN

被引：34

作者：

DAVIES, MJ ^{[1
]}

MOODY, CJ ^{[1
]}

机构：

[1] IMPERIAL COLL SCI TECHNOL & MED,DEPT CHEM,LONDON SW7 2AY,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 01期

关键词：

D O I：

10.1039/p19910000009

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The cis-2,7-disubstituted oxepane skeleton 1 of the marine natural product isolaurepinnacin 2 has been obtained by three routes, all of which involve a rhodium (II) acetate mediated cyclisation of diazo alcohols to give the functionalised oxepanes 3, 4 and 5, suitable for further elaboration into the common intermediate, the oxepan-3-one 8.

引用

页码：9 / 12

页数：4

共 39 条

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