BETA-GLOBIN GENE-CLUSTER HAPLOTYPES OF AMERINDIAN POPULATIONS FROM THE BRAZILIAN AMAZON REGION

被引：24

作者：

GUERREIRO, JF ^{[1
]}

FIGUEIREDO, MS ^{[1
]}

ZAGO, MA ^{[1
]}

机构：

[1] UNIV SAO PAULO,DEPT CLIN MED,BR-14049900 RIBEIRAO PRET,BRAZIL

来源：

HUMAN HEREDITY | 1994年 / 44卷 / 03期

关键词：

BETA-GLOBIN GENE HAPLOTYPES; DNA POLYMORPHISMS; SOUTH AMERICAN INDIANS; HEMOGLOBIN;

D O I：

10.1159/000154206

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We have determined the beta-golobin cluster haplotypes for 80 Indians from four Brazilian Amazon tribes: Kayapo, Wayampi, Wayana-Apalai, and Arara. The results are analyzed together with 20 Yanomami previously studied. From 2 to 4 different haplotypes were identified for each tribe, and 7 of the possible 32 haplotypes were found in a sample of 172 chromosomes for which the beta haplotypes were directly determined or derived from family studies. The haplotype distribution does not differ significantly among the five populations. The two most common haplotypes in all tribes were haplotypes 2 and 6, with average frequencies of 0.843 and 0.122, respectively. The genetic affinities between Brazilian Indians and other human populations were evaluated by estimates of genetic distance based on haplotype data. The lowest values were observed in relation to Asians, especially Chinese, Polynesians, and Micronesians.

引用

页码：142 / 149

页数：8

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