ELIMINATION DIET AND INTESTINAL PERMEABILITY IN ATOPIC ECZEMA - A PRELIMINARY-STUDY

被引:41
作者
CAFFARELLI, C
CAVAGNI, G
MENZIES, IS
BERTOLINI, P
ATHERTON, DJ
机构
[1] ST THOMAS HOSP,LONDON SE1 7EH,ENGLAND
[2] HOSP SICK CHILDREN,LONDON WC1N 3JH,ENGLAND
关键词
D O I
10.1111/j.1365-2222.1993.tb02480.x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
We measured small intestinal permeability to lactulose and rhamnose in 18 healthy children and in 15 children with atopic eczema, before and after a 14-day elimination diet. The children with atopic eczema had higher initial urinary lactulose/rhamnose ratios than the controls. After dietary restriction, there was no overall change in permeability. Dietary therapy did however result in a large reduction in permeability in three of the nine children whose skin disease was improved, but a statistically significant decrease in permeability was not observed in the diet-responsive group as a whole. Larger studies would be required to confirm that dietary restrictions can reduce intestinal permeability in some children with atopic eczema.
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页码:28 / 31
页数:4
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