MORPHOMETRIC STUDIES USING NEUROIMAGING

Quantitative methods are being employed to characterize cerebral and cerebellar morphology in pediatric neurogenetic syndromes. Although such brain morphometry is a relatively recent endeavor, the field is enjoying a steady advance in its methodology and power. Morphometric studies on Rett, Down, Williams, and other neurogenetic syndromes illustrate progress in the field. In the future, brain morphometry has the potential to contribute both diagnostic and prognostic information for clinical practice, and to help advance the understanding of the brain mechanisms that underlie behavior.