REACTOGENICITY AND IMMUNOGENICITY OF A SURFACE-ANTIGEN-ADSORBED INFLUENZA-VIRUS VACCINE IN CHILDREN

被引：13

作者：

EASTWOOD, LM

JENNINGS, R

MILNER, RDG

POTTER, CW

机构：

[1] UNIV SHEFFIELD, DEPT VIROL, ACADEM DIV PATHOL, SHEFFIELD S10 2RX, S YORKSHIRE, ENGLAND

[2] CHILDRENS HOSP, DEPT PEDIAT, SHEFFIELD S10 2TH, S YORKSHIRE, ENGLAND

来源：

JOURNAL OF CLINICAL PATHOLOGY | 1979年 / 32卷 / 06期

关键词：

D O I：

10.1136/jcp.32.6.534

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

An influenza virus vaccine containing the purified surface haemagglutinin and neuraminidase antigens of A/Victoria/75 and B/Hong Kong/73 viruses adsorbed to an aluminium hydroxide gel was assessed for reactogenicity and immunogenicity in children aged 4 to 11 years, since there is no influenza virus vaccine avaible for this age group. Significant serum haemagglutination-inhibiting antibody responses to the A/Victoria/75 and B/Hong Kong/73 haemagglutinin antigens present in the vaccine were observed in 47% and 35%, respectively, of the children vaccinated, with a single dose. The vaccine induced no significant local or systemic reactions.

引用

页码：534 / 537

页数：4

共 21 条

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