PNEUMOCYSTIS-CARINII PNEUMONIA AFTER HEART-TRANSPLANTATION

被引：14

作者：

SAIGENJI, H ^{[1
]}

KANEKO, M ^{[1
]}

RHENMEN, B ^{[1
]}

WILLIAMS, RJ ^{[1
]}

VASU, MA ^{[1
]}

ICENOGLE, TB ^{[1
]}

COPELAND, JG ^{[1
]}

机构：

[1] UNIV ARIZONA,ARIZONA HLTH SCI CTR,DEPT SURG,CARDIOVASC & THORAC SURG SECT,1501 N CAMPBELL AVE,TUCSON,AZ 85724

来源：

ANNALS OF THORACIC SURGERY | 1991年 / 52卷 / 01期

关键词：

ACQUIRED IMMUNODEFICIENCY SYNDROME; DIAGNOSIS; SPUTUM; AIDS;

D O I：

10.1016/0003-4975(91)91429-Y

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Five patients with Pneumocystis carinii pneumonia after heart transplantation are reported. Four had severe clinical symptoms, whereas 1 was asymptomatic. Mechanical ventilatory support was necessary in 1 because of respiratory distress. Pneumocystis carinii infection developed in 4 patients within the first 4 postoperative months, and 1 patient had clinical disease 1 year after transplantation with a recurrence 9 months later. All were treated with trimethoprim-sulfamethoxazole either orally or intravenously (10 to 20 mg.kg-1.day-1 of trimethoprim). All patients recovered from infection and received the same drug prophylactically for 2 to 20 months after the infection. All patients are doing well after Pneumocystis carinii infection except 1 who died after an acute myocardial infarction 4 years after infection. We conclude that trimethoprim-sulfamethoxazole is an effective agent for the treatment of Pneumocystis carinii pneumonia after heart transplantation.

引用

页码：107 / 111

页数：5