POSTSPLENECTOMY INFECTIONS

被引：10

作者：

COLE, JT

FLAUM, MA

机构：

[1] Department of Internal Medicine, Section on Hematology and Oncology, Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans, LA

[2] St. Joseph Mercy Hospital, Department of Internal Medicine, Ann Arbor, MI

来源：

SOUTHERN MEDICAL JOURNAL | 1992年 / 85卷 / 12期

关键词：

D O I：

10.1097/00007611-199212000-00014

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Serious postsplenectomy infection is a significant threat to patients. Although the incidence of such infection is low, the resultant mortality is extremely high. This susceptibility to infection and ensuing mortality results from multiple immunologic changes that occur after splenectomy. These changes include alteration in immunoglobulin levels, loss of serum opsonizing proteins, and alterations in antigen clearance and cellular immunity.

引用

页码：1220 / 1226

页数：7

共 74 条

[51]

NIELSEN JL, 1982, SCAND J HAEMATOL, V29, P168

[52] ANTIGENS IN IMMUNITY .12. ANTIGEN TRAPPING IN SPLEEN [J].

NOSSAL, GJV ;

AUSTIN, CM ;

PYE, J ;

MITCHELL, J .

INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY, 1966, 29 (04) :368-+

[53] THE RISK OF SEPSIS IN THE ASPLENIC ADULT [J].

ONEAL, BJ ;

MCDONALD, JC .

ANNALS OF SURGERY, 1981, 194 (06) :775-778

[54]

PATEL J, 1981, SURGERY, V90, P683

[55] BORN-AGAIN SPLEEN - RETURN OF SPLENIC FUNCTION AFTER SPLENECTOMY FOR TRAUMA [J].

PEARSON, HA ;

JOHNSTON, D ;

SMITH, KA ;

TOULOUKIAN, RJ .

NEW ENGLAND JOURNAL OF MEDICINE, 1978, 298 (25) :1389-1392

[56]

Ramsay L E, 1973, J R Nav Med Serv, V59, P102

[57] MULTIPLE COAGULATIVE DEFECTS IN A PATIENT WITH WATERHOUSE-FRIDERICHSEN SYNDROME [J].

RATNOFF, OD ;

NEBEHAY, WG .

ANNALS OF INTERNAL MEDICINE, 1962, 56 (04) :627-+

[58]

RICE HM, 1980, LANCET, V1, P565

[59] NORMAL RESPONSE OF SICKLE CELL ANEMIA PATIENTS TO IMMUNIZATION WITH SALMONELLA VACCINES [J].

ROBBINS, JB ;

PEARSON, HA .

JOURNAL OF PEDIATRICS, 1965, 66 (05) :877-+

[60]

ROBINETTE CD, 1977, LANCET, V2, P127

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