COMPARATIVE BIOLOGICAL PROPERTIES OF HA PLASMA-SPRAYED COATINGS HAVING DIFFERENT CRYSTALLINITIES

被引：67

作者：

FRAYSSINET, P ^{[1
]}

TOURENNE, F ^{[1
]}

ROUQUET, N ^{[1
]}

CONTE, P ^{[1
]}

DELGA, C ^{[1
]}

BONEL, G ^{[1
]}

机构：

[1] CHU TOULOUSE PURPAN,SERV CHIRURG ORTHOPED,TOULOUSE,FRANCE

来源：

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 1994年 / 5卷 / 01期

关键词：

D O I：

10.1007/BF00121147

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Plasma-sprayed HA-coatings used for orthopaedic surgery can contain different percentages of crystalline phase. The influence of the amount of crystalline and amorphous phase on the biological properties of coatings is not known. The aim of this study is to determine the effect of this coating characteristic on mammalian cell functions in vitro. It appears that 100% crystalline coatings have an inhibiting effect on cell proliferation and on alkaline phosphatase activity. A direct contact of the cells with the material is necessary to obtain this effect. The material evolves during the period of culture. Poorly crystalline coatings dissolve during the period of culture and the roughness parameters change during the same period.

引用

页码：11 / 17

页数：7

共 14 条

[1] ADOLPHE M, 1988, CULTURE CELLULES ANI, P1
[2] ALBERTS B, 1989, MOL BIOL CELL, P682
[3] CALCIUM AND THE CYTOSKELETON
BENNETT, J
WEEDS, A
[J]. BRITISH MEDICAL BULLETIN, 1986, 42 (04) : 385 - 390
[4] BERRIDGE MJ, 1982, NATURE, V312, P315
[5] COOK SD, 1988, CLIN ORTHOP RELAT R, V232, P225
[6] DARD M, 1991, B GROUP INT RECHERCH, V35, P209
[7] TOXICITY OF HYDROXYAPATITE INVITRO - THE EFFECT OF PARTICLE-SIZE
EVANS, EJ
[J]. BIOMATERIALS, 1991, 12 (06) : 574 - 576
[8] EVANS RW, 1982, CLIN RES, V30, pA805
[9] FRAYSSINET P, 1990, LIMB SALVAGE MAJOR R, P169
[10] McAteer J A, 1979, Methods Enzymol, V58, P132

← 1 2 →