AN INVITRO CHARACTERIZATION OF INTERSTRAND CROSS-LINKS IN DNA EXPOSED TO THE ANTI-TUMOR DRUG CIS-DICHLORODIAMMINEPLATINUM(II)

被引：18

作者：

DEUTSCH, WA ^{[1
]}

SPIERING, AL ^{[1
]}

NEWKOME, GR ^{[1
]}

机构：

[1] LOUISIANA STATE UNIV,DEPT CHEM,BATON ROUGE,LA 70803

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1980年 / 97卷 / 03期

关键词：

D O I：

10.1016/0006-291X(80)91505-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1220 / 1226

页数：7

共 9 条

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[2]

DEUTSCH WA, 1979, J BIOL CHEM, V254

[3] THIOUREA REVERSES CROSS-LINKS AND RESTORES BIOLOGICAL-ACTIVITY IN DNA TREATED WITH DICHLORODIAMINOPLATINUM(II) [J].

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[4] BINDING OF PLATINUM AND PALLADIUM METALLOINTERCALATION REAGENTS AND ANTITUMOR DRUGS TO CLOSED AND OPEN DNAS [J].

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[6]

LEGERSKI RJ, 1977, J BIOL CHEM, V252, P8740

[7] ANTI-TUMOR AGENTS - SYNTHESIS OF NOVEL CIS-PALLADIUM COMPLEXES AND THEIR ACTION ON SUPERCOILED DNA [J].

NEWKOME, GR ;

ONISHI, M ;

PUCKETT, WE ;

DEUTSCH, WA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (13) :4551-4552

[8]

Roberts J J, 1979, Prog Nucleic Acid Res Mol Biol, V22, P71, DOI 10.1016/S0079-6603(08)60799-0

[9]

ZWELLING LA, 1979, CANCER RES, V39, P4989

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