EFFECTS OF ENGINEERING COMPLEMENTARY CHARGED RESIDUES INTO THE HYDROPHOBIC SUBUNIT INTERFACE OF TYROSYL-TRANSFER RNA-SYNTHETASE

被引：19

作者：

WARD, WHJ ^{[1
]}

JONES, DH ^{[1
]}

FERSHT, AR ^{[1
]}

机构：

[1] UNIV LONDON IMPERIAL COLL SCI & TECHNOL,DEPT CHEM,LONDON SW7 2AY,ENGLAND

来源：

BIOCHEMISTRY | 1987年 / 26卷 / 13期

关键词：

D O I：

10.1021/bi00387a058

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：4131 / 4138

页数：8

共 24 条

[1] ROLE OF A BURIED ACID GROUP IN MECHANISM OF ACTION OF CHYMOTRYPSIN [J].

BLOW, DM ;

BIRKTOFT, JJ ;

HARTLEY, BS .

NATURE, 1969, 221 (5178) :337-&

[2]

BLOW DM, 1985, BIOL MACROMOL, V2, P442

[3] MOLECULAR-STRUCTURE OF CRYSTALLINE STREPTOMYCES-GRISEUS PROTEASE-A AT 2.8-A RESOLUTION .2. MOLECULAR-CONFORMATION, COMPARISON WITH ALPHA-CHYMOTRYPSIN AND ACTIVE-SITE GEOMETRY [J].

BRAYER, GD ;

DELBAERE, LTJ ;

JAMES, MNG .

JOURNAL OF MOLECULAR BIOLOGY, 1978, 124 (01) :261-283

[4] PURIFICATION AND PHYSICAL CHARACTERIZATION OF TYROSYL RIBONUCLEIC ACID SYNTHETASES FROM ESCHERICHIA COLI AND BACILLUS SUBTILIS [J].

CALENDAR, R ;

BERG, P .

BIOCHEMISTRY, 1966, 5 (05) :1681-&

[5] METHIONYL-T-RNA SYNTHETASE FROM WHEAT EMBRYO - DISSOCIATION INTO SUBUNITS [J].

CHAZAL, P ;

THOMES, JC ;

JULIEN, R .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1977, 73 (02) :607-615

[6]

Fersht A, 1985, ENZYME STRUCTURE MEC

[7] HYDROGEN-BONDING AND BIOLOGICAL SPECIFICITY ANALYZED BY PROTEIN ENGINEERING [J].

FERSHT, AR ;

SHI, JP ;

KNILLJONES, J ;

LOWE, DM ;

WILKINSON, AJ ;

BLOW, DM ;

BRICK, P ;

CARTER, P ;

WAYE, MMY ;

WINTER, G .

NATURE, 1985, 314 (6008) :235-238

[8] ACTIVE-SITE TITRATION AND AMINOACYL ADENYLATE BINDING STOICHIOMETRY OF AMINOACYL-TRANSFER-RNA SYNTHETASES [J].

FERSHT, AR ;

ASHFORD, JS ;

BRUTON, CJ ;

JAKES, R ;

KOCH, GLE ;

HARTLEY, BS .

BIOCHEMISTRY, 1975, 14 (01) :1-4

[9] STABILITY OF SALT BRIDGES IN MEMBRANE-PROTEINS [J].

HONIG, BH ;

HUBBELL, WL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (17) :5412-5416

[10] TRYPTOPHANYL-TRANSFER RIBONUCLEIC-ACID SYNTHETASE FROM BEEF PANCREAS - LIGAND BINDING AND DISSOCIATION EQUILIBRIUM BETWEEN ACTIVE DIMERIC AND INACTIVE MONOMERIC STRUCTURES [J].

IBORRA, F ;

DORIZZI, M ;

LABOUESS.J .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1973, 39 (01) :275-282

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