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BRAIN MACROPHAGES - NEUROTOXIC OR NEUROTROPHIC EFFECTOR-CELLS

被引：109
作者：
MALLAT, M
CHAMAK, B
机构：
[1] INSERM U.114, College de France, 75231 Paris Cedex 05, 11, Place Marcelin Berthelot
来源：
JOURNAL OF LEUKOCYTE BIOLOGY | 1994年 / 56卷 / 03期
关键词：
NEURONAL DEATH; MICROGLIA; CENTRAL NERVOUS SYSTEM; DEVELOPMENT;
D O I：
10.1002/jlb.56.3.416
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 [细胞生物学]; 090102 [作物遗传育种];
摘要：
The development of the central nervous system and various pathological contexts imply remodeling or alteration of neuronal networks associated with tissue recruitment of mononuclear phagocytes. Purification and culture of brain macrophages have provided a tool for investigating the functions of these cells. We discuss different mechanisms whereby macrophages could directly influence the survival of neurons and the growth of their processes.
引用
收藏
页码：416 / 422
页数：7
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