RETRO-COPE ELIMINATIONS IN THE SYNTHESIS OF 1,2,5-OXADIAZINANES FROM ALLYLAMINES AND NITRONES - A METHOD FOR THE AMINATION OF UNACTIVATED ALKENES

被引：38

作者：

GRAVESTOCK, MB

KNIGHT, DW

THORNTON, SR

机构：

[1] ICI AGROCHEM, JEALOTTS HILL RES STN, BRACKNELL RG12 3EY, BERKS, ENGLAND

[2] CHEM DEPT, NOTTINGHAM NG7 2RD, ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1993年 / 02期

关键词：

D O I：

10.1039/c39930000169

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Heating an allylamine (e.g. 9) and a nitrone (e.g. 10) in an inert solvent produces often excellent yields of a 1,2,5-oxadiazinane (e.g. 11) by a pathway which features a retro-Cope elimination and a Meisenheimer rearrangement; reduction of the oxadiazinanes leads to vicinal diamines and hence overall amination of the alkene function in the original allylamine.

引用

页码：169 / 171

页数：3

共 22 条

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