CARBANION METHODOLOGY FOR ALKYLATIONS AND ACYLATIONS IN THE SYNTHESIS OF SUBSTITUTED OXAZOLES - THE FORMATION OF CORNFORTH REARRANGEMENT PRODUCTS

被引：10

作者：

WILLIAMS, DR

MCCLYMONT, EL

机构：

[1] Department of Chemistry, Indiana University Bloomington

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 48期

关键词：

OXAZOLE SYNTHESIS; CORNFORTH REARRANGEMENT;

D O I：

10.1016/S0040-4039(00)61544-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Studies of monoalkylation of the dianion generated from 2-(5-oxazolyl)-1,3-dithiane 1 led exclusively to substitution adjacent to sulfur. However, acylation reactions of 1 afforded 4,5-disubstituted oxazoles as novel examples of direct acylation of the oxazole nucleus.

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页码：7705 / 7708

页数：4

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