PARVALBUMIN-IMMUNOREACTIVE CORTICAL-NEURONS IN CREUTZFELDT-JAKOB-DISEASE

被引：38

作者：

FERRER, I

CASAS, R

RIVERA, R

机构：

[1] Unidad de Neuropatología, Servicio de Anatomía Patológica, Hospital Prícipes de España, Universidad de Barcelona, Barcelona

来源：

ANNALS OF NEUROLOGY | 1993年 / 34卷 / 06期

关键词：

D O I：

10.1002/ana.410340617

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Massive abnormalities of parvalbumin-immunoreactive cortical neurons were observed in the cerebral biopsy samples of 3 patients with Creutzfeldt-Jakob disease. Immunoreactive cells had reduced and short, often fragmented, dendrites, and large numbers of dendritic varicosities were observed. Since parvalbumin-immunoreactive neurons are the most important inhibitory cells in the cerebral cortex, the damage to these neurons may account, in part, for the impaired cortical function, and may play a role in the appearance of myoclonus and electroencephalographic patterns in patients with Creutzfeldt-Jakob disease.

引用

页码：864 / 866

页数：3

共 15 条

[1] CALCIUM-BINDING PROTEINS - SELECTIVE MARKERS OF NERVE-CELLS
ANDRESSEN, C
BLUMCKE, I
CELIO, MR
[J]. CELL AND TISSUE RESEARCH, 1993, 271 (02) : 181 - 208
[2] CREUTZFELDT-JAKOB DISEASE - CLINICAL ANALYSIS OF A CONSECUTIVE SERIES OF 230 NEUROPATHOLOGICALLY VERIFIED CASES
BROWN, P
CATHALA, F
CASTAIGNE, P
GAJDUSEK, DC
[J]. ANNALS OF NEUROLOGY, 1986, 20 (05) : 597 - 602
[3] CALBINDIN D-28K AND PARVALBUMIN IMMUNOREACTIVITY IN THE FRONTAL-CORTEX IN PATIENTS WITH FRONTAL-LOBE DEMENTIA OF NON-ALZHEIMER TYPE ASSOCIATED WITH AMYOTROPHIC-LATERAL-SCLEROSIS
FERRER, I
TUNON, T
SERRANO, MT
CASAS, R
ALCANTARA, S
ZUJAR, MJ
RIVERA, RM
[J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1993, 56 (03) : 257 - 261
[4] PARVALBUMIN IMMUNOREACTIVE NEURONS IN NORMAL HUMAN TEMPORAL NEOCORTEX AND IN PATIENTS WITH ALZHEIMERS-DISEASE
FERRER, I
SORIANO, E
TUNON, T
FONSECA, M
GUIONNET, N
[J]. JOURNAL OF THE NEUROLOGICAL SCIENCES, 1991, 106 (02) : 135 - 141
[5] ABNORMAL LOCAL-CIRCUIT NEURONS IN EPILEPSIA PARTIALIS CONTINUA ASSOCIATED WITH FOCAL CORTICAL DYSPLASIA
FERRER, I
PINEDA, M
TALLADA, M
OLIVER, B
RUSSI, A
OLLER, L
NOBOA, R
ZUJAR, MJ
ALCANTARA, S
[J]. ACTA NEUROPATHOLOGICA, 1992, 83 (06) : 647 - 652
[6] CREUTZFELDT-JACOB DISEASE - A GOLGI-STUDY
FERRER, I
COSTA, F
VECIANA, JMG
[J]. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 1981, 7 (03) : 237 - 242
[7] FERRER I, IN PRESS NEUROSCI LE
[8] CHANDELIER CELL AXONS IDENTIFIED BY PARVALBUMIN-IMMUNOREACTIVITY IN THE NORMAL HUMAN TEMPORAL CORTEX AND IN ALZHEIMERS-DISEASE
FONSECA, M
SORIANO, E
FERRER, I
MARTINEZ, A
TUNON, T
[J]. NEUROSCIENCE, 1993, 55 (04) : 1107 - 1116
[9] HENDRY SHC, 1989, EXP BRAIN RES, V76, P467
[10] PARVALBUMIN-IMMUNOREACTIVE NEURONS IN THE NEOCORTEX ARE RESISTANT TO DEGENERATION IN ALZHEIMERS-DISEASE
HOF, PR
COX, K
YOUNG, WG
CELIO, MR
ROGERS, J
MORRISON, JH
[J]. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1991, 50 (04) : 451 - 462

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