LACK OF EFFECT OF BUTYLATED HYDROXYTOLUENE ON DIMETHYLHYDRAZINE-INDUCED COLON CARCINOGENESIS IN RATS

被引：8

作者：

BARBOLT, TA

ABRAHAM, R

机构：

[1] Center of Experimental Pathology and Toxicology, Albany Medical College, Albany, 12208, New York

来源：

EXPERIENTIA | 1979年 / 35卷 / 02期

关键词：

D O I：

10.1007/BF01920650

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Rats were given 6600 ppm of butylated hydroxytoluene (BHT) in the diet along with 10 weekly oral doses of dimethylhydrazine (DMH, 30 mg/kg). The incidence and mean number of colonic tumors produced were similar to that of rats given DMH alone. Thus, BHT did not provide any protective effect against colon carcinogenesis. © 1979 Birkhäuser Verlag.

引用

页码：257 / 258

页数：2

共 14 条

[11] WARD JM, 1974, LAB INVEST, V30, P505
[12] WATTENBERG LW, 1972, JNCI-J NATL CANCER I, V48, P1425
[13] INHIBITION OF DIMETHYLHYDRAZINE-INDUCED NEOPLASIA OF LARGE-INTESTINE BY DISULFIRAM
WATTENBERG, LW
[J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1975, 54 (04) : 1005 - 1006
[14] INHIBITORY EFFECT OF BUTYLATED HYDROXYTOLUENE (BHT) ON INTESTINAL CARCINOGENESIS IN RATS BY AZOXYMETHANE
WEISBURGER, EK
EVARTS, RP
WENK, ML
[J]. FOOD AND COSMETICS TOXICOLOGY, 1977, 15 (02): : 139 - 141

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