CYTOGENETIC ANALYSIS OF LYMPHOCYTES FROM HOSPITAL WORKERS OCCUPATIONALLY EXPOSED TO LOW-LEVELS OF IONIZING-RADIATION

被引：85

作者：

BARQUINERO, JF

BARRIOS, L

CABALLIN, MR

MIRO, R

RIBAS, M

SUBIAS, A

EGOZCUE, J

机构：

[1] UNIV AUTONOMA BARCELONA,HOSP SANTA CREU & SANT PAU,SERV ONCOL,E-08193 BARCELONA,SPAIN

[2] UNIV AUTONOMA BARCELONA,HOSP SANTA CREU & SANT PAU,INST BIOL FONAMENTAL,E-08193 BARCELONA,SPAIN

[3] UNIV AUTONOMA BARCELONA,HOSP SANTA CREU & SANT PAU,DEPT BIOL CELLULAR & FISIOL,E-08193 BARCELONA,SPAIN

[4] UNIV AUTONOMA BARCELONA,HOSP SANTA CREU & SANT PAU,DEPT BIOL ANIM BIOL VEGETAL & ECOL,E-08193 BARCELONA,SPAIN

来源：

MUTATION RESEARCH | 1993年 / 286卷 / 02期

关键词：

OCCUPATIONAL EXPOSURE; CHROMOSOME ABERRATIONS; PERIPHERAL BLOOD LYMPHOCYTES;

D O I：

10.1016/0027-5107(93)90192-I

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Cytogenetic studies were performed in lymphocytes from hospital workers exposed to low doses of radiation (1.6-42.71 mSv). When compared with controls, exposed workers showed a significant increase in structural chromosome-type aberrations, acentric fragments being the most frequent alteration. Our results suggest that acentric fragments are good indicators of exposure to very low doses of radiation, although no dose-effect correlation was observed. The incidence of numerical abnormalities (hyperdiploidy) was significantly increased.

引用

页码：275 / 279

页数：5

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