ACTH-INDUCED HYPERALGESIA IN RATS

被引：83

作者：

BERTOLINI, A

POGGIOLI, R

FERRARI, W

机构：

[1] Institute of Pharmacology, University of Modena, Modena, I-41100

来源：

EXPERIENTIA | 1979年 / 35卷 / 09期

关键词：

D O I：

10.1007/BF01963298

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The injection of ACTH 1-24 into the cerebral ventricles in rats markedly reduces the reaction time in the hotplate test and the nociception threshold in the tail-stimulation test. Morphine antagonizes and naloxone potentiates this hyperalgesic effect of ACTH. It is proposed that ACTH peptides play a physiological role in nociception. © 1979 Birkhäuser Verlag.

引用

页码：1216 / 1217

页数：2

共 52 条

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