HODGKINS-DISEASE

被引：72

作者：

DESFORGES, JF

RUTHERFORD, CJ

PIRO, A

机构：

[1] NEW ENGLAND MED CTR HOSP, DEPT THERAPEUT RADIOL, BOSTON, MA 02111 USA

[2] TUFTS UNIV, SCH MED, BOSTON, MA 02111 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 1979年 / 301卷 / 22期

关键词：

D O I：

10.1056/NEJM197911293012205

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

SINCE Hodgkin's disease was last considered in detail in this journal1 impressive progress has been made in understanding discrete aspects of the disease. Evidence has accumulated in support of a monocyte-macrophage origin for the malignant cell, while immune suppression has been implicated in the disturbed cellular immunity that characterizes Hodgkin's disease. Some evidence from these immunologic studies, together with genetic and family surveys, hints at a genetic proclivity for immune suppression that may predispose to Hodgkin's disease, but the pathogenesis of the disease remains unknown. The newer strategies for staging and treatment can now be evaluated, and the earlier optimistic. © 1979, Massachusetts Medical Society. All rights reserved.

引用

页码：1212 / 1222

页数：11

共 163 条

[11]

BERETTA G, 1976, CANCER TREAT REP, V60, P1231

[12] HODGKINS-DISEASE - ULTRASTRUCTURAL LOCALIZATION OF INTRA-CYTOPLASMIC IMMUNOGLOBULINS WITHIN MALIGNANT CELLS [J].