Y-CHROMOSOME LOSS IN LEUKEMIAS

被引:38
作者
BERGER, R
BERNHEIM, A
机构
[1] Laboratoire de Cytogénétique, Institut de Recherches sur les Leucémies, Hôpital Saint-Louis, Paris
关键词
D O I
10.1016/0165-4608(79)90003-7
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Four cases of leukemia with a missing Y cell line are reported: one of chronic myeloid leukemia in blastic crisis; one of polycythemia vera terminating in acute myeloblastic leukemia, where the missing Y was observed prior to leukemia and was associated with other chromosome abnormalities in the leukemic phase; one of acute myelomonocytic leukemia; and one acute lymphocytic leukemia with, respectively, partial and complete reappearance of the Y chromosome on leukemia remission. The possible significance of the loss of the Y in leukemic cells is discussed. © 1979.
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页码:1 / 8
页数:8
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