YEAST DNA-POLYMERASES AND THEIR ROLE AT THE REPLICATION FORK

被引：100

作者：

SUGINO, A

机构：

[1] Department of Biochemistry and Molecular Biology, Research Institute for Microbial Diseases, Osaka University, 565, 3-1 Yamada-Oka, suita Osaka

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1995年 / 20卷 / 08期

关键词：

D O I：

10.1016/S0968-0004(00)89059-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The DNA polymerases of the yeast Saccharomyces cerevisiae serve as a model system for the study of the replication fork during DNA replication. To date, six S. cerevisiae DNA polymerases have been at least partially characterized (compared with four in mammals so far), with further candidates being identified as open reading frames in the yeast genome sequencing project. Here, we review the current state of knowledge of the yeast polymerases, and discuss, where possible, their biological role during DNA replication.

引用

页码：319 / 323

页数：5

共 40 条

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