兰屿树杞(Ardisia cf. elliptica)三萜及其抑制鸭(Anas platyrynchos L.)绒毛尿囊膜血管生成作用(英文)

被引：2

作者：

Dennis D Raga ^{[1
,2
]}

Annabelle A Herrera ^{[2
]}

Consolacion Y Ragasa ^{[3
]}

机构：

[1] Biology Department, School of Science and Engineering, Ateneo de Manila University

[2] Institute of Biology, University of the Philippines

[3] Chemistry Department and Center for Natural Sciences and Ecological Research, De La Salle University

来源：

中国天然药物 | 2013年 / 11卷 / 02期

关键词：

D O I：

暂无

中图分类号：

R285 [中药药理学];

学科分类号：

100806 [中药药理学];

摘要：

The dichloromethane extract of the air-dried leaves of Ardisia cf.elliptica(subgenus Tinus)afforded a mixture of bauerenol(1a),α-amyrin(1b)andβ-amyrin(1c).Their structures were identified by NMR spectroscopy.Mixtures of the triterpenes (1a-1c)at ratios of 2:2:1,2:2:3 and 1:1:1 were tested for their angio-suppressive effects on duck chorioallantoic membrane (CAM).All three ratios were found to be effective in restricting inter-capillary length,while 1a-1c(2:2:1)was most effective in reducing branch point density with 100%CAM viability and embryo survivability,suggesting a high impact angio-suppressive potential of 1a-1c(2:2:1).

引用

页码：128 / 138

页数：11

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