肠道吻合愈合研究进展

被引：23

作者：

黄从云

彭淑牖

机构：

[1] 浙江大学医学院附属第二医院普外科

[2] 浙江大学医学院附属第二医院普外科杭州

[3] 杭州

来源：

国外医学外科学分册. | 2005年 / 02期

关键词：

肠道吻合; 胶原代谢;

D O I：

暂无

中图分类号：

R656.7 [小肠];

学科分类号：

100201 [内科学];

摘要：

肠道吻合愈合过程中胶原代谢受MMP、TIMP、NOS和胶原基因等调控。不同部位的胶原合成能力不同 ,小肠胶原合成能力明显高于结肠。结肠胶原合成能力基本一致 ,小肠近段、远段胶原合成能力比中段强。肠道吻合后 ,结肠胶原降解比小肠明显、持久。腹腔感染、糖尿病、肠梗阻和放疗等通过不同途径调节胶原代谢而影响肠道吻合愈合

引用

页码：114 / 119

页数：6

共 9 条

[1]

Experimental colonic obstruction increases collagen degradation by matrix metalloproteinases in the bowel wall [J].

Syk, I ;

Mirastschijski, U ;

Jeppsson, BW ;

Ågren, MS .

DISEASES OF THE COLON & RECTUM, 2003, 46 (09) :1251-1259

[2]

Arginase acts as an alternative pathway of L-arginine metabolism in experimental colon anastomosis [J].

Witte, MB ;

Vogt, N ;

Stuelten, C ;

Gotoh, T ;

Mori, M ;

Becker, HD .

JOURNAL OF GASTROINTESTINAL SURGERY, 2003, 7 (03) :378-385

[3]

Intestinal anastomoses from diabetic rats contain supranormal levels of gelatinase activity [J].

Verhofstad, NHJ ;

Lomme, RMLM ;

de Man, BM ;

Hendriks, T .

DISEASES OF THE COLON & RECTUM, 2002, 45 (04) :554-561

[4]

Prevention of deleterious effects of reperfusion injury using one-week high-dose allopurinol [J].

Terzi, C ;

Kuzu, MA ;

Kessaf, A ;

Kale, IT ;

Tanik, A ;

Köksoy, C .

DIGESTIVE DISEASES AND SCIENCES, 2001, 46 (02) :430-437

[5]

The effect of intraoperative colonic lavage with NG-nitro-L-arginine methyl ester (L-NAME) on anastomotic healing in the presence of left-sided colonic obstruction in the rat [J].

Erbil, Y ;

Çalis, A ;

Berber, E ;

Mercan, S .

SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY, 2000, 30 (05) :421-425

[6]

Expression and function of inducible nitric oxide synthase during rat colon anastomotic healing [J].

Efron, DT ;

Thornton, FJ ;

Steulten, C ;

Tantry, US ;

Witte, MB ;

Kiyama, T ;

Barbul, A .

JOURNAL OF GASTROINTESTINAL SURGERY, 1999, 3 (06) :592-601

[7]

Intraoperative bowel irrigation improves anastomotic collagen metabolism in the left-sided colonic obstruction but not covering colostomy [J].

Duraker, N ;

Bender, Ö ;

Memisoglu, K ;

Yalçiner, A .

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 1998, 13 (5-6) :232-234

[8]

TISSUE OXYGEN-TENSION AS A PREDICTOR OF COLONIC ANASTOMOTIC HEALING [J].

SHERIDAN, WG ;

LOWNDES, RH ;

YOUNG, HL .

DISEASES OF THE COLON & RECTUM, 1987, 30 (11) :867-871

[9]

Colonic anastomotic strength and matrix metalloproteinase activity in an experimental model of bacterial peritonitis..de Hingh IH; de Man BM; Lomme RM; et al;.Br J Surg.2003,

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