Toll样受体研究进展

被引：55

作者：

于高水

杨玉荣

梁宏德

机构：

[1] 河南农业大学牧医工程学院

来源：

细胞生物学杂志 | 2009年 / 31卷 / 03期

关键词：

Toll样受体; 免疫; 结构; 配体; 信号通路;

D O I：

暂无

中图分类号：

R392 [医学免疫学];

学科分类号：

100108 [医学免疫学];

摘要：

Toll样受体(Toll like receptors,TLRs)是近年发现并倍受关注的一种识别受体。人们发现其在先天性和获得性免疫应答过程中起到链接点的作用,因此,TLRs在免疫学领域内具有重要地位。目前对TLRs的研究涉及到其结构、配体、信号通路以及临床应用等。现就TLRs目前的研究进展作一综述。

引用

页码：339 / 343

页数：5

共 10 条

[1]

Toll-NF-κB信号途径及其介导的功能 [J].

杨玉荣 ;

佘锐萍 ;

梁宏德 .

细胞生物学杂志, 2007, (04) :483-486

[2]

N-acetylcysteine inhibits activation of toll-like receptor 2 and 4 gene expression in the liver and lung after partial hepatic ischemia-reperfusion injury in mice.[J]..Hepatobiliary & Pancreatic Diseases International.2007, 03

[3]

Autophagy and toll-like receptors: A new link in cancer cells.[J].Samuel Bertin;Valérie Pierrefite-Carle.Autophagy.2008, 8

[4]

Toll-Like Receptor 6 Drives Differentiation of Tolerogenic Dendritic Cells and Contributes to LcrV-Mediated Plague Pathogenesis [J].

DePaolo, R. William ;

Tang, Fangming ;

Kim, InYoung ;

Han, Mei ;

Levin, Nadine ;

Ciletti, Nancy ;

Lin, Anning ;

Anderson, Debra ;

Schneewind, Olaf ;

Jabri, Bana .

CELL HOST & MICROBE, 2008, 4 (04) :350-361

[5]

The role of innate immune receptors in the control of Brucella abortus infection: Toll-like receptors and beyond [J].

Oliveira, Sergio Costa ;

de Oliveira, Fernanda Souza ;

Macedo, Gilson Costa ;

de Almeida, Leonardo Augusto ;

Carvalho, Natalia Barbosa .

MICROBES AND INFECTION, 2008, 10 (09) :1005-1009

[6]

Ketamine Suppresses Intestinal TLR4 Expression and NF-κB Activity in Lipopolysaccharide-treated Rats.[J].Min Yu;Shangwu Feng;Jianjun Yang;Danbing Shao;Jianguo Xu.Croatian Medical Journal.2006, 6

[7]

Flagellin suppresses epithelial apoptosis and limits disease during enteric infection [J].

Vijay-Kumar, Matam ;

Wu, Huixia ;

Jones, Rheinallt ;

Grant, George ;

Babbin, Brian ;

King, Timothy P. ;

Kelly, Denise ;

Gewirtz, Andrew T. ;

Neish, Andrew S. .

AMERICAN JOURNAL OF PATHOLOGY, 2006, 169 (05) :1686-1700

[8]

Detrimental Contribution of the Toll-Like Receptor (TLR)3 to Influenza A Virus–Induced Acute Pneumonia.[J].Ronan Le Goffic;Viviane Balloy;Micheline Lagranderie;Lena Alexopoulou;Nicolas Escriou;Richard Flavell;Michel Chignard;Mustapha Si-Tahar.PLOS Pathogens.2006, 6

[9]

Toll-like receptors.[J].H Shaw Warren.Critical Care Medicine.2005, 12 S

[10]

Toll-like receptors: sensors of the innate immune system [J].

Seitz, M .

ALLERGY, 2003, 58 (12) :1247-1249

← 1 →