间充质干细胞在组织再生应用中的诸多问题

被引:34
作者
王恒湘 [1 ]
郭子宽 [2 ]
机构
[1] 空军总医院血液科
[2] 北京放射与辐射医学研究所实验血液学研究室
关键词
D O I
暂无
中图分类号
R329 [人体组织学];
学科分类号
100107 [人体解剖与组织胚胎学(人体解剖学、组织与胚胎学)];
摘要
<正>间充质干细胞(Mesenchymal stem cells,MSC)是一种主要存在于骨髓的未分化多能细胞,具有分化为多种结缔组织细胞的潜能,可分化为成骨细胞、软骨细胞、脂肪细胞、基质细胞、成纤维细胞和肌腱细胞等。在机体正常的组织损伤修复过程中,MSC是一种重要的参与组织再生的细胞库。在组织损伤
引用
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页码:241 / 245
页数:5
相关论文
共 21 条
[1]
Immunomodulation by mesenchymal stem cells - A potential therapeutic strategy for type 1 diabetes [J].
Abdi, Reza ;
Fiorina, Paolo ;
Adra, Chaker N. ;
Atkinson, Mark ;
Sayegh, Mohamed H. .
DIABETES, 2008, 57 (07) :1759-1767
[2]
A novel rich source of human mesenchymal stem cells from the debris of bone marrow samples [J].
Jin, Ji-De ;
Wang, Heng-Xiang ;
Xiao, Feng-Jun ;
Wang, Jin-Song ;
Lou, Xiao ;
Hu, Liang-Ding ;
Wang, Li-Sheng ;
Guo, Zi-Kuan .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 376 (01) :191-195
[3]
Comparison of osteogenic ability of rat mesenchymal stem cells from bone marrow, periosteum, and adipose tissue [J].
Hayashi, Ousuke ;
Katsube, Yoshihiro ;
Hirose, Motohiro ;
Ohgushi, Hajime ;
Ito, Hiromoto .
CALCIFIED TISSUE INTERNATIONAL, 2008, 82 (03) :238-247
[4]
Tumor microenvironment: The role of the tumor stroma in cancer [J].
Li, Hanchen ;
Fan, Xueli ;
Houghton, JeanMarie .
JOURNAL OF CELLULAR BIOCHEMISTRY, 2007, 101 (04) :805-815
[5]
Mesenchymal stem cells from rat bone marrow downregulate caspase-3-mediated apoptotic pathway after spinal cord injury in rats [J].
Dasari, Venkata Ramesh ;
Spomar, Daniel G. ;
Cady, Craig ;
Gujrati, Meena ;
Rao, Jasti S. ;
Dinh, Dzung H. .
NEUROCHEMICAL RESEARCH, 2007, 32 (12) :2080-2093
[6]
Malignant gliomas actively recruit bone marrow stromal cells by secreting angiogenic cytokines [J].
Birnbaum, Tobias ;
Roider, Julia ;
Schankin, Christoph J. ;
Padovan, Claudio S. ;
Schichor, Christian ;
Goldbrunner, Roland ;
Straube, Andreas .
JOURNAL OF NEURO-ONCOLOGY, 2007, 83 (03) :241-247
[7]
Comparison of rat mesenchymal stem cells derived from bone marrow, synovium, periosteum, adipose tissue, and muscle [J].
Yoshimura, Hideya ;
Muneta, Takeshi ;
Nimura, Akimoto ;
Yokoyama, Akiko ;
Koga, Hideyuki ;
Sekiya, Ichiro .
CELL AND TISSUE RESEARCH, 2007, 327 (03) :449-462
[8]
Vascular fate of adipose tissue-derived adult stromal cells in the ischemic murine brain: A combined imaging-histological study.[J].Nathalie Kubis;Yutaka Tomita;Alexy Tran-Dinh;Valérie Planat-Benard;Mireille André;Bartosz Karaszewski;Ludovic Waeckel;Luc Pénicaud;Jean-Sébastien Silvestre;Louis Casteilla;Jacques Seylaz;Elisabeth Pinard.Neuroimage.2006, 1
[9]
Investigation of multipotent postnatal stem cells from human periodontal ligament [J].
Seo, BM ;
Miura, M ;
Gronthos, S ;
Bartold, PM ;
Batouli, S ;
Brahim, J ;
Young, M ;
Robey, PG ;
Wang, CY ;
Shi, ST .
LANCET, 2004, 364 (9429) :149-155
[10]
Establishment of tendon-derived cell lines exhibiting pluripotent mesenchymal stem cell-like property [J].
Salingcarnboriboon, R ;
Yoshitake, H ;
Tsuji, K ;
Obinata, M ;
Amagasa, T ;
Nifuji, A ;
Noda, M .
EXPERIMENTAL CELL RESEARCH, 2003, 287 (02) :289-300