Design of a novel polymeric heart valve

被引：31

作者：

Burriesci G. ^{[1
]}

Marincola F.C. ^{[1
]}

Zervides C. ^{[1
]}

机构：

[1] Cardiovascular Engineering and Medical Devices Group, Department of Mechanical Engineering, UCL, WC1E 7JE, London, Torrington Place

来源：

Journal of Medical Engineering and Technology | 2010年 / 34卷 / 01期

基金：

英国工程与自然科学研究理事会;

关键词：

Design optimization; Finite elements; Heart valve design; Polymeric heart valves;

D O I：

10.3109/03091900903261241

中图分类号：

学科分类号：

摘要：

Polymeric heart valves could offer an optimum alternative to current prostheses, by joining the advantages of mechanical and bioprosthetic valves. Though a number of materials suitable for this application have recently become available, significant improvements in the valve design are still needed. In this paper, a novel polymeric heart valve design is proposed and its optimization procedure, based on the use of finite elements, is described. The design strategy was aimed at reducing the energy absorbed during the operating cycle, resulting in high hydrodynamic performances and reduced stress levels. The efficacy of the design strategy was assessed by comparing the valve dynamics and stress levels predicted numerically during the cycle with those of an existing and well qualified polymeric valve design. The improved hydrodynamic performance of the proposed design was confirmed experimentally, by in vitro testing in a pulse duplicator. © 2009 Informa UK Ltd.

引用

页码：7 / 22

页数：15

共 67 条

[41]

Wheatley D.J., Raco L., Bernacca G.M., Sim I., Belcher P.R., Boyd J.S., Polyurethane: Material for the next generation heart valve prosthes?, European Journal of Cardio-thoracic Surgery, 17, pp. 440-448, (2000)

[42]

Gorlin R., Gorlin S.G., Hydraulic formula for calculation of stenotic mitral valve, other cardiac valves, and central circulatory shunts, American Heart Journal, 41, pp. 1-29, (1951)

[43]

Burriesci G., Howard I.C., Patterson E.A., Influence of anisotropy on the mechanical behaviour of bioprosthetic heart valves, Journal of Medical Engineering & Technology, 23, pp. 203-215, (1999)

[44]

Carmody C.J., Burriesci G., Howard I.C., Patterson E.A., The use of LS-DYNA fluid-structure interaction to simulate fluiddriven deformation in the aortic valve, Proceedings of the 4th European LS-DYNA Conference, (2003)

[45]

Carmody C.J., Burriesci G., Howard I.C., Patterson E.A., An approach to the simulation of fluid-structure interaction in the aortic valve, Journal of Biomechanics, 39, pp. 158-169, (2006)

[46]

Mooney M., A Theory of large elastic deformation, Journal of Applied Physics, 11, pp. 582-592, (1940)

[47]

Rivlin R.S., Saunders D.W., Large elastic deformations of isotropic materials, VII, experiments on the deformation of rubber, Transactions of the Royal Society of London

[48]

Series A (Mathematical and Physical Sciences), 243, pp. 251-288, (1951)

[49]

Ogden R.W., Large deformation isotropic elasticity: On the correlation of theory and experiment for compressible rubberlike solids, Proceedings of the Royal Society of London

[50]

Series A, Mathematical and Physical Sciences, 328, pp. 567-583, (1972)

← 1 2 3 4 5 6 7 →