Cryogenically cooled probes - A leap in NMR technology

被引：378

作者：

Kovacs, Helena ^{[1
]}

Moskau, Detlef ^{[1
]}

Spraul, Manfred ^{[2
]}

机构：

[1] Bruker BioSpin AG, CH-8117 Fällanden

[2] Bruker BioSpin AG, D-76287 Rheinstetten, Silberstreifen

来源：

Progress in Nuclear Magnetic Resonance Spectroscopy | 2005年 / 46卷 / 2-3期

关键词：

Cryogenic probe technology; NMR (Nuclear Magnetic Resonance); Sensitivity; Signal-to-noise ratio;

D O I：

10.1016/j.pnmrs.2005.03.001

中图分类号：

学科分类号：

摘要：

The recent innovation of cryogenically cooled probes for high-resolution NMR spectroscopy enables a three-fold enhancement of the detection sensitivity in high-resolution NMR compared to conventional probes. The probe houses a preamplifier to amplify the detected signals. The sensitivity or signal-to-noise enhancement in the cryogenic probe is accomplished by lowering the temperature of the coil and the preamplifier. The probes are available for operation with 5 and 3 mm diameter sample tubes and also for LC-NMR, and flow injection modes. The technology is regarded as an example of the interdependence of technological innovation and market demand.

引用

页码：131 / 155

页数：24

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