Regulation of endocytic traffic by Rho GTPases

被引：49

作者：

Qualmann, Britta ^{[1
]}

Mellor, Harry ^{[2
]}

机构：

[1] Dept. of Neurochem./Molec. Biology, Leibniz Institute for Neurobiology

[2] Mammalian Cell Biology Laboratory, Department of Biochemistry, University of Bristol

来源：

Biochemical Journal | 2003年 / 371卷 / 02期

关键词：

Actin; Endocytosis; Migration; Phagocytosis; Pinocytosis;

D O I：

10.1042/BJ20030139

中图分类号：

学科分类号：

摘要：

The members of the Rho subfamily of small GTPases are key regulators of the actin cytoskeleton. However, recent studies have provided evidence for multiple additional roles for these signalling proteins in controlling endocytic traffic. Here we review our current understanding of Rho GTPase action within the endocytic pathway and examine the potential points of convergence with the more established, actin-based functions of these signalling proteins.

引用

页码：233 / 241

页数：8

共 116 条

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