基于影像学腰椎退变的生物力学有限元分析

被引:1
作者
高升 [1 ]
辛世民 [2 ]
刘兴权 [1 ]
亢利清 [3 ]
任宝林 [1 ]
王海燕 [4 ]
机构
[1] 呼和浩特市中医蒙医医院医学影像科
[2] 七台河职业学院医疗卫生系
[3] 内蒙古自治区第四医院消毒供应中心
[4] 内蒙古医科大学基础医学院解剖教研室
关键词
腰椎退变; 骨赘; 有限元分析; 应力分布; 力学响应;
D O I
暂无
中图分类号
R681.5 [脊柱及背疾病]; R318.01 [生物力学];
学科分类号
100103 [病原生物学]; 100220 [骨科学];
摘要
背景:腰椎退化会引起腰痛,了解导致腰椎退变引起疼痛的潜在力学机制是至关重要的。目的:分析正常与退变腰椎在力学性能上的区别,为进一步探寻腰椎退变机制及其相关疗法提供依据。方法:基于健康、腰椎退变男性受试者的腰椎CT图像进行三维重建,建立L1-S1有限元模型。对正常与退变腰椎的生物力学特性进行有限元分析,通过加载生理条件,重点分析前屈、后伸、左右侧屈、左右旋转6个运动范围的差异,评估具有椎体前缘骨赘的有限元模型在不同运动模式下的腰椎整体、各节段活动范围及椎骨、纤维环、髓核、小关节应力分布。结果与结论:(1)退化腰椎整体活动范围和节段活动范围均出现了不同程度的下降,特别是在后伸和侧屈运动中,退化的腰椎表现出显著的活动受限;(2)腰椎的退化改变了力学的环境,邻近节段的椎骨、椎间盘与小关节应力均增大;(3)腰椎退变导致活动度下降,特别影响后伸和侧屈运动;(4)L4节段在退变后承受了更高的应力,可能是下腰痛的关键因素;(5)退变腰椎的力学负荷重分配对邻近节段影响显著。
引用
收藏
页码:3810 / 3819
页数:10
相关论文
共 42 条
[31]
Posteriorly Directed Shear Loads and Disc Degeneration Affect the Torsional Stiffness of Spinal Motion Segments A Biomechanical Modeling Study [J].
Homminga, Jasper ;
Lehr, Anne M. ;
Meijer, Gerdine J. M. ;
Janssen, Michiel M. A. ;
Schlosser, Tom P. C. ;
Verkerke, Gijsbertus J. ;
Castelein, Rene M. .
SPINE, 2013, 38 (21) :E1313-E1319
[32]
Effects of degenerated intervertebral discs on intersegmental rotations, intradiscal pressures, and facet joint forces of the whole lumbar spine [J].
Park, Won Man ;
Kim, Kyungsoo ;
Kim, Yoon Hyuk .
COMPUTERS IN BIOLOGY AND MEDICINE, 2013, 43 (09) :1234-1240
[33]
Instability of the lumbar spine due to disc degeneration. A finite element simulation.[J].Elena Ibarz;Yolanda Más;Jesús Mateo;Antonio Lobo-Escolar;Antonio Herrera;Luis Gracia.Advances in Bioscience and Biotechnology.2013, 4
[34]
The mechanical response of the lumbar spine to different combinations of disc degenerative changes investigated using randomized poroelastic finite element models [J].
Galbusera, Fabio ;
Schmidt, Hendrik ;
Neidlinger-Wilke, Cornelia ;
Gottschalk, Andreas ;
Wilke, Hans-Joachim .
EUROPEAN SPINE JOURNAL, 2011, 20 (04) :563-571
[35]
Do early stages of lumbar intervertebral disc degeneration really cause instability? Evaluation of an in vitro database [J].
Kettler, Annette ;
Rohlmann, F. ;
Ring, C. ;
Mack, C. ;
Wilke, H-J .
EUROPEAN SPINE JOURNAL, 2011, 20 (04) :578-584
[36]
Biomechanical role of lumbar spine ligaments in flexion and extension: Determination using a parallel linkage robot and a porcine model [J].
Gillespie, KA ;
Dickey, JP .
SPINE, 2004, 29 (11) :1208-1216
[37]
Osteoarthritis: Is it a disease of cartilage or of bone? [J].
Felson, DT ;
Neogi, T .
ARTHRITIS AND RHEUMATISM, 2004, 50 (02) :341-344
[38]
The effect of disc degeneration and facet joint osteoarthritis on the segmental flexibility of the lumbar spine [J].
Fujiwara, A ;
Lim, TH ;
An, HS ;
Tanaka, N ;
Jeon, CH ;
Andersson, GBJ ;
Haughton, VM .
SPINE, 2000, 25 (23) :3036-3044
[39]
Low back pain in relation to lumbar disc degeneration [J].
Luoma, K ;
Riihimäki, H ;
Luukkonen, R ;
Raininko, R ;
Viikari-Juntura, E ;
Lamminen, A .
SPINE, 2000, 25 (04) :487-492
[40]
The relationship between disc degeneration, facet joint osteoarthritis, and stability of the degenerative lumbar spine [J].
Fujiwara, A ;
Tamai, K ;
An, HS ;
Kurihashi, A ;
Lim, TH ;
Yoshida, H ;
Saotome, K .
JOURNAL OF SPINAL DISORDERS, 2000, 13 (05) :444-450