左背外侧前额叶阳极经颅直流电刺激对脑卒中后抑郁症的疗效观察

被引:33
作者
邓家丰 [1 ]
张静娜 [1 ]
肖府庭 [2 ]
肖明月 [1 ]
汪洁 [3 ]
机构
[1] 北京和睦家康复医院
[2] 武汉市第一医院
[3] 首都医科大学宣武医院
关键词
经颅直流电刺激; 抑郁症; 脑卒中; 日常生存质量;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)]; R749.4 [情感性精神病];
学科分类号
100204 [神经病学];
摘要
目的:观察左背外侧前额叶阳极经颅直流电刺激对脑卒中后抑郁症的疗效。方法:将40例脑卒中患者随机分成治疗组与对照组各20例,观察治疗4周。治疗组在常规康复治疗的基础上在第1周及第2周每日增加阳极经颅直流电刺激左背外侧前额叶治疗,对照组只进行常规的康复治疗训练。在经颅直流电刺激介入前及第1周、第2周、第4周后分别应用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、改良Barthel指数(MBI)、工具性日常生活能力量表(IADL)评定患者心理及日常生活能力改善效果。结果:治疗组患者经颅直流电刺激(t DCS)治疗1周、2周后的HAMA、HAMD评分均明显低于对照组,而且差异具有显著性意义(P<0.05);且在刺激结束2周后的随访对比中明显要优于对照组。结论:阳极经颅直流电刺激左背外侧前额叶对脑卒中后抑郁症可减轻或消除脑卒中患者的抑郁或者焦虑情绪,提高患者的日常生存质量。
引用
收藏
页码:556 / 561
页数:6
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