杓型和非杓型高血压病患者动脉重构的改变

被引：7

作者：

魏玉杰

刘惠亮

段媛媛

马聪

荆丽敏

机构：

[1] 武警总医院心内科

来源：

中华老年多器官疾病杂志 | 2008年 / 7卷 / 06期

关键词：

高血压; 昼夜节律; 动脉; 重构;

D O I：

暂无

中图分类号：

R544.1 [高血压];

学科分类号：

100201 [内科学];

摘要：

目的通过比较杓型与非杓型原发性高血压患者动脉重构的参数变化,探讨原发性高血压患者血压节律类型与动脉重构的相关性。方法选取1、2级原发性高血压患者128例,行动态血压监测,根据夜间平均动脉压下降10%以上或以下的标准分为杓型组(56例)与非杓型组(72例),应用彩色多普勒超声检测颈总动脉内膜中层厚度(IMT)、脉搏波速度测定仪同时检测颈动脉-桡动脉(C-RPWV)、颈动脉-股动脉(C-FPWV)的脉搏波速度,测定血清中内皮素1(ET-1)和一氧化氮(NO)浓度。比较两组间上述检测指标。结果非杓型组IMT较杓型组明显增厚;C-RPWV和C-FPWV在非杓型组明显高于杓型组;血清ET-1浓度在非杓型组明显高于杓型组,而NO浓度低于杓型组,两因子在两组间比较具有统计学差异。结论非杓型血压较杓型血压对动脉结构及功能的影响可能更明显。

引用

页码：489 / 491

页数：3

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