Wnt信号通路在肿瘤调控方面的研究进展

被引:93
作者
张世蘋
张旭
机构
[1] 南京中医药大学江苏省中医药防治肿瘤协同创新中心
关键词
Wnt信号通路; β-catenin; APC蛋白; 信号通路的调节; 机制; 肿瘤;
D O I
暂无
中图分类号
R73-3 [肿瘤学实验研究];
学科分类号
100214 [肿瘤学];
摘要
Wnt信号通路是一条进化上十分保守的信号通路,控制着细胞的生长、分化、凋亡和自我更新。在肿瘤的发生发展中,该通路常常异常激活,并能够和其他信号通路协同或拮抗调节肿瘤的增殖、迁移和侵袭。该文主要对Wnt信号通路的研究进展及其在各类肿瘤生长调控中的作用进行简要综述。
引用
收藏
页码:14 / 18
页数:5
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