脂肪来源干细胞对增生性瘢痕影响的实验研究进展

被引：7

作者：

赵诗艺 ^{[1
,2
]}

常鹏 ^{[1
]}

郭冰玉 ^{[1
]}

王飏 ^{[1
,2
]}

陶凯 ^{[1
]}

机构：

[1] 北部战区总医院整形外科

[2] 大连医科大学附属第二医院

来源：

中国美容整形外科杂志 | 2019年 / 30卷 / 07期

关键词：

脂肪来源干细胞; 增生性瘢痕; 瘢痕治疗;

D O I：

暂无

中图分类号：

R622 [整形手术学];

学科分类号：

100224 [整形外科学];

摘要：

增生性瘢痕是机体在创伤后的愈合过程中发生异常修复而形成突出于皮肤表面的瘢痕组织。近年来,应用脂肪来源干细胞(adipose-derived stem cells,ADSCs)治疗和预防增生性瘢痕已成为一种很有前景的治疗方法。ADSCs可以通过免疫调节、中和活性氧、分泌抗纤维化的细胞因子和生长因子、调节成纤维细胞以及分化为各种皮肤细胞等参与正常皮肤创伤的修复,达到抑制瘢痕和修复的作用。现回顾近年发表的文献,对ADSCs治疗增生性瘢痕的可能机制作一综述。

引用

页码：414 / 415+440 +440

页数：3

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