松质骨显微结构参数与表观力学强度关系研究进展

被引：11

作者：

温鑫鑫

雷伟

王法琪

王军

吴子祥

严亚波

机构：

[1] 第四军医大学西京医院骨科

来源：

中国骨质疏松杂志 | 2014年 / 20卷 / 12期

关键词：

骨质疏松; 松质骨; 骨密度; 显微结构; 骨强度;

D O I：

暂无

中图分类号：

R580 [];

学科分类号：

摘要：

通过双能X射线吸收法测量受试者的骨密度,是目前公认的诊断骨质疏松症的方法。然而,越来越多的基础和临床研究发现,骨密度的改变并不能完全解释患者骨强度的改变。大量的骨组织显微结构研究发现,松质骨的骨强度主要由骨密度、骨结构等因素决定。近年来的研究表明,在决定松质骨骨骼强度方面,骨组织的显微结构可以作为独立于骨密度之外的决定性参数。研究松质骨的力学属性和显微结构之间的关系,对于更好的理解骨质疏松的发生和对骨质疏松的诊断具有十分重要的意义。根据文献回顾,松质骨显微结构参数和表观力学强度之间关联性最为显著的为BV/TV、Tb.N、连接性、各向异性、结构模型指数等。同时笔者也对目前这些研究结果在临床上高分辨率CT上的应用情况做一总结。

引用

页码：1495 / 1500+1510 +1510

页数：7

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