体内真菌毒素生物标记物检测方法的研究进展

被引：4

作者：

谢丽伟 ^{[1
,2
]}

孔维军 ^{[2
]}

杨美华 ^{[2
]}

欧阳臻 ^{[1
]}

机构：

[1] 江苏大学药学院

[2] 中国医学科学院中国协和医科大学

来源：

世界科学技术-中医药现代化 | 2013年 / 15卷 / 03期

关键词：

真菌毒素生物标记物; 体内; 检测技术;

D O I：

暂无

中图分类号：

R379 [病原真菌（霉菌）与放线菌];

学科分类号：

摘要：

真菌毒素是一些真菌在生长过程中产生的有毒次级代谢产物,广泛污染农作物、食品和饲料等,由于多数真菌毒素具有很强的毒性,可致癌、致畸和致突变,人和动物通过饮食可能暴露于不同的真菌毒素,对人和动物的健康构成了极大的威害。本文以人和动物血液、尿液、胆汁、乳汁和粪便中真菌毒素的原形及其代谢物作为真菌毒素生物标记物,通过测定其含量来评价人和动物暴露于真菌毒素的频率和水平。本文归纳体内常见真菌毒素生物标记物的种类,分析其对人和动物的危害性,并综述体内真菌毒素生物标记物检测的研究现状。

引用

页码：543 / 550

页数：8

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