脑网络:从脑结构到脑功能

被引:166
作者
蒋田仔
刘勇
李永辉
机构
[1] 中国科学院自动化研究所,模式识别国家重点实验室,LIAMA计算医学研究中心
关键词
弥散张量成像; 功能磁共振成像; 复杂脑网络;
D O I
暂无
中图分类号
R338 [神经生理学]; R318 [生物医学工程];
学科分类号
100103 [病原生物学]; 100115 [医学神经生物学];
摘要
越来越多的证据表面脑连接反映了信息在脑内的处理过程,但是,到目前未知,我们还没有完全理解脑连接和脑内信息动态处理之间的复杂关系。本文从脑结构到脑功能方面介绍了从不同模态影像学数据构造脑网络的主要进展。我们首先给出了网络的基本定义,然后分别介绍了利用DTI构造结构网络,利用fMRI构造功能网络的方法。随后,我们探讨了不同的脑疾病(特别是阿尔茨海默病和精神分裂症)患者脑网络拓扑结构是否发生了异常,最后对本领域未来的研究做了简单的展望。
引用
收藏
页码:181 / 188
页数:8
相关论文
共 18 条
[1]
Studying the human brain anatomical network via diffusion-weighted MRI and Graph Theory [J].
Iturria-Medina, Yasser ;
Sotero, Roberto C. ;
Canales-Rodriguez, Erick J. ;
Aleman-Gomez, Yasser ;
Melie-Garcia, Lester .
NEUROIMAGE, 2008, 40 (03) :1064-1076
[2]
Network analysis of intrinsic functional brain connectivity in Alzheimer's disease [J].
Supekar, Kaustubh ;
Menon, Vinod ;
Rubin, Daniel ;
Musen, Mark ;
Greicius, Michael D. .
PLOS COMPUTATIONAL BIOLOGY, 2008, 4 (06)
[3]
Small-world network topology of hippocampal neuronal network is lost, in an in vitro glutamate injury model of epilepsy [J].
Srinivas, Kalyan V. ;
Jain, Rishabh ;
Saurav, Subit ;
Sikdar, Sujit K. .
EUROPEAN JOURNAL OF NEUROSCIENCE, 2007, 25 (11) :3276-3286
[4]
Efficiency and cost of economical brain functional networks [J].
Achard, Sophie ;
Bullmore, Edward T. .
PLOS COMPUTATIONAL BIOLOGY, 2007, 3 (02) :174-183
[5]
Small-world networks and disturbed functional connectivity in schizophrenia.[J].Sifis Micheloyannis;Ellie Pachou;Cornelis Jan Stam;Michael Breakspear;Panagiotis Bitsios;Michael Vourkas;Sophia Erimaki;Michael Zervakis.Schizophrenia Research.2006, 1
[6]
Using graph theoretical analysis of multi channel EEG to evaluate the neural efficiency hypothesis [J].
Micheloyannis, Sifis ;
Pachou, Ellie ;
Stam, Cornelis J. ;
Vourkas, Michael ;
Erimaki, Sophia ;
Tsirka, Vasso .
NEUROSCIENCE LETTERS, 2006, 402 (03) :273-277
[7]
Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging [J].
Liang, M ;
Zhou, Y ;
Jiang, TZ ;
Liu, ZN ;
Tian, LX ;
Liu, HH ;
Hao, YH .
NEUROREPORT, 2006, 17 (02) :209-213
[8]
The human connectome:: A structural description of the human brain [J].
Sporns, O ;
Tononi, G ;
Kötter, R .
PLOS COMPUTATIONAL BIOLOGY, 2005, 1 (04) :245-251
[9]
Diffusion tensor imaging in schizophrenia [J].
Kanaan, RAA ;
Kim, JS ;
Kaufmann, WE ;
Pearlson, GD ;
Barker, GJ ;
McGuire, PK .
BIOLOGICAL PSYCHIATRY, 2005, 58 (12) :921-929
[10]
Organization, development and function of complex brain networks [J].
Sporns, O ;
Chialvo, DR ;
Kaiser, M ;
Hilgetag, CC .
TRENDS IN COGNITIVE SCIENCES, 2004, 8 (09) :418-425