食品是如何通过细胞因子网络控制人类健康的(II)

被引:19
作者
庞广昌
陈庆森
胡志和
机构
[1] 天津商学院生物技术与食品科学学院
关键词
细胞因子网络; 免疫学; 食品科学; 发炎细胞因子; 抗炎细胞因子; 理论模型;
D O I
暂无
中图分类号
R151 [营养学];
学科分类号
100403 ;
摘要
本文的目的是要有选择性地综述食品和肠粘膜、Toll样受体、细胞因子网络和免疫系统的相互作用。越来越多的研究结果显示,少量的食物蛋白、多肽、脂肪、低聚糖和其他生化物质可以诱导或抑制两种-发炎细胞因子和抗炎细胞因子两者之一,从而进一步地控制先天或后天获得性免疫系统、神经生理和代谢网络。而且越来越充分的证据表明,发炎和抗炎细胞因子之间的平衡和联系与中医中药中所说的“阴”“阳”之间的协调与平衡十分相似。中国人一直用“阴”“阳”来分类食品和药品,而且他们坚信一个人可以通过保持他们的食品和中草药的食入和“阴”“阳”平衡来改善其健康状况,治病防病。所以,本文在这些广泛的实验依据的基础上提出了一个理论模型,用来解释食品是如何通过对细胞因子网络的作用来调控免疫网络,并进而影响人体健康的。
引用
收藏
页码:260 / 270
页数:11
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共 30 条
[21]   Alcohol and cytokine networks [J].
Deaciuc, IV .
ALCOHOL, 1997, 14 (05) :421-430
[22]  
Fatty acid composition of lymphocytes and macrophages from rats fed fiber-rich diets: A comparison between oat bran- and wheat bran-enriched diets[J] . C. R. Cavaglieri Felippe,P. C. Calder,M. G. Vecchia,M. R. Campos,J. Mancini-Filho,E. A. Newsholme,R. Curi.Lipids . 1997 (6)
[23]   Anorexia induced by chronic central administration of cytokines at estimated pathophysiological concentrations [J].
PlataSalaman, CR ;
Sonti, G ;
Borkoski, JP ;
Wilson, CD ;
FfrenchMullen, JMH .
PHYSIOLOGY & BEHAVIOR, 1996, 60 (03) :867-875
[24]  
The role of tumor necrosis factor-α in the pathogenesis of anorexia and bulimia nervosa, cancer cachexia and obesity[J] . R.J. Holden,I.S. Pakula.Medical Hypotheses . 1996 (6)
[25]  
Peripheral administration of interleukin-1 increases extracellular concentrations of norepinephrine in rat hypothalamus: Comparison with plasma corticosterone[J] . Gennady N. Smagin,Artur H. Swiergiel,Adrian J. Dunn.Psychoneuroendocrinology . 1996 (1)
[26]  
The expanding universe of T-cell subsets: Th1, Th2 and more[J] . Tim R. Mosmann,Subash Sad.Immunology Today . 1996 (3)
[27]   Immunoendocrine aspects of anorexia nervosa [J].
Brambilla, F ;
Ferrari, E ;
Brunetta, M ;
Peirone, A ;
Draisci, A ;
Sacerdote, P ;
Panerai, A .
PSYCHIATRY RESEARCH, 1996, 62 (01) :97-104
[28]  
Cytokines and the nervous system I: expression and recognition[J] . Stephen J. Hopkins,Nancy J. Rothwell.Trends in Neurosciences . 1995 (2)
[29]   LOW LYMPHOCYTE INTERFERON-GAMMA PRODUCTION AND VARIABLE PROLIFERATIVE RESPONSE IN ANOREXIA-NERVOSA PATIENTS [J].
POLACK, E ;
NAHMOD, VE ;
EMERICSAUVAL, E ;
BELLO, M ;
COSTAS, M ;
FINKIELMAN, S ;
ARZT, E .
JOURNAL OF CLINICAL IMMUNOLOGY, 1993, 13 (06) :445-451
[30]  
Down-regulation of tumor necrosis factor α activity by acute ethanol treatment in human peripheral blood monocytes[J] . Bikash K. Verma,Miklos Fogarasi,Gyongyi Szabo.Journal of Clinical Immunology . 1993 (1)