ADH1B和ALDH2基因多态性与相关疾病研究进展

被引：15

作者：

张晓敏

刘静

高世超

杨婷婷

王培昌

机构：

[1] 首都医科大学宣武医院检验科

来源：

检验医学 | 2019年 / 34卷 / 03期

关键词：

乙醇脱氢酶1B; 乙醛脱氢酶2; 基因多态性; 疾病;

D O I：

暂无

中图分类号：

R440 [];

学科分类号：

摘要：

乙醇脱氢酶(ADH)和乙醛脱氢酶(ALDH)是人体肝脏内乙醇代谢的关键酶,共同构成ADH氧化体系。ADH1B和ALDH2分别是ADH和ALDH的2个重要亚型。ADH1B和ALDH2基因多态性与多种疾病,如消化系统疾病、神经退行性变及代谢性疾病等相关。文章对ADH1B及ALDH2基因多态性与相关疾病的关系进行综述,以期为疾病的预防和诊断提供新的思路。

引用

收藏

页码：271 / 275

页数：5

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