肿瘤免疫逃逸机制的研究进展

被引:88
作者
阎永贞
那可
魏晓东
金媛媛
赵波
赵文杰
机构
[1] 中国医药工业研究总院上海医药工业研究院创新药物与制药工艺国家重点实验室
关键词
肿瘤细胞; 树突状细胞; 免疫抑制因子; 免疫逃逸;
D O I
暂无
中图分类号
R730.3 [肿瘤免疫学与血清学];
学科分类号
100108 [医学免疫学];
摘要
机体中偶然出现的肿瘤细胞可被免疫细胞所识别,并作为异物而加以清除,但肿瘤在机体的免疫监视下仍能产生、发展和转移,表明肿瘤具有免疫逃逸的能力。本文综述了肿瘤免疫过程中肿瘤抗原表达、识别、加工、递呈、T细胞增殖、活化和分化以及免疫效应的产生等一系列环节中肿瘤免疫逃逸机制的研究进展。
引用
收藏
页码:619 / 624
页数:6
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